Publications
A Uropathogenic E. Coli UTI89 Model of Prostatic Inflammation and Collagen Accumulation for Use in Studying Aberrant Collagen Production in the Prostate
Ruetten H, Sandhu J, Mueller B, Wang P, Zhang HL, Wegner KA, Cadena M, Sandhu S, L Abler L, Zhu J, O'Driscoll CA, Chelgren B, Wang Z, Shen T, Barasch J, Bjorling DE, Vezina CM. Am J Physiol Renal Physiol. 2021 Jan 1;320(1):F31-F46. doi: 10.1152/ajprenal.00431.2020. Epub 2020 Nov 2. PMID: 33135480
Mutations in Transcription Factor CP2-like 1 May Cause a Novel Syndrome With Distal Renal Tubulopathy in Humans
Klämbt V, Werth M, Onuchic-Whitford AC, Getwan M, Kitzler TM, Buerger F, Mao Y, Deutsch K, Mann N, Majmundar AJ, Kaminski MM, Shen T, Schmidt-Ott KM, Shalaby M, El Desoky S, Kari JA, Shril S, Lienkamp SS, Barasch J, Hildebrandt F. Nephrology Dial Transplant. 2021 Jan 25;36(2):237-246. doi: 10.1093/ndt/gfaa215. PMID: 33097957
Carbapenemase-producing Enterobacterales Causing Secondary Infections During the COVID-19 Crisis at a New York City Hospital
Gomez-Simmonds A, Annavajhala MK, McConville TH, Dietz DE, Shoucri SM, Laracy JC, Rozenberg FD, Nelson B, Greendyke WG, Furuya EY, Whittier S, Uhlemann AC. J Antimicrob Chemother. 2021 Jan 19;76(2):380-384. doi: 10.1093/jac/dkaa466. PMID: 33202023 Free PMC article.
Copy Number Variant Analysis and Genome-Wide Association Study Identify Loci With Large Effect for Vesicoureteral Reflux
Verbitsky M., Krithivasan P., Batourina E., Khan,A., Graham S. E., Marasa M, Kim, H., Weng, P. L., Sanchez-Rodrigues, E., Mitrotti, A., Ahram, D., Zanoni, F., Fasel, D., Westland, R., Sampson, M. G., Zhang, J. Y., Bodria, M., Kil, B. H., Shri, S., Gesualdo, L., Torri, F., Scolari, F., Izzi, C., van Wijk, J. A., Saraga-Babic, M., Santoro, D., Conti, C., Barton, D., Dobson, M. G., Puri, P., Furth, S. L., Warady, B. A., Pisani, I., Fiaccadori, E., Allegri, L., Degl’Innocenti, M. L., Plaggio, G., Alam, S., Gigante, B., Zaza, G., Esposito, C., Lin, F., Simões-e-Silva, A. C., Brodkiewicz, A., Drozdz, D., Zachwieja, K., Miklaszewska, M., Szczepanska, M., Adamczyk, P., Tkaczyk, M., Tomczyk, D., Sikora, P., Mizerska-Wasiak, M., Krzemien, G., Szmigielska, A., Zaniew, M., Lozanovski, V. J., Gucev, Z., Ionita-Laza, I., Stanaway, I., Crosslin, D., Wong, C., Hildebrand, M. S., Barasch, J., Kenny, E., Loos, R. J., Levy, B., Ghiggeri, G., Hakonarson, H., Latos-Bielenska, A., Materna-Kiryluk, A., Darlow, J. M., Tasic, V., Willeit, J., Kiryluk, K., Sanna-Cherchi, S., Mendelsohn, C. & Gharavi, A.G*. J. Am. Soc. Nephrol. 2020 in press.
Rare Genetic Causes of Complex Kidney and Urological Diseases
Groopman, EE, Povysil G, Goldstein DB, Gharavi AG. Nat Reviews Nephr. 2020, 16(11):641-656.
CrrB Positively Regulates High-Level Polymyxin Resistance and Virulence in Klebsiella pneumoniae
McConville TH, Annavajhala MK, Giddins MJ, Macesic N, Herrera CM, Rozenberg FD, Bhushan GL, Ahn D, Mancia F, Trent MS, Uhlemann AC. Cell Reports. 2020 Oct 27;33(4):108313. doi: 10.1016/j.celrep.2020.108313. PMID: 33113377 Free PMC article.
Evolution of the Environmental Microbiota of a New Neonatal Intensive Care Unit (NICU) and Implications for Infection Prevention and Control
Zachariah P, Rozenberg FD, Stump S, Moscoso DI, Krishnamurthy G, Saiman L, Uhlemann AC, Freedberg DE. Infect Control Hosp Epidemiol. 2020 Aug 28:1-6. doi: 10.1017/ice.2020.396. Online ahead of print. PMID: 32856577
Predicting Phenotypic Polymyxin Resistance in Klebsiella pneumoniae through Machine Learning Analysis of Genomic Data
Macesic N, Bear Don't Walk OJ IV, Pe'er I, Tatonetti NP, Peleg AY, Uhlemann AC. mSystems. 2020 May 26;5(3):e00656-19. doi: 10.1128/mSystems.00656-19. PMID: 32457240 Free PMC article.
Pseudomonas aeruginosa Utilizes Host-Derived Itaconate to Redirect Its Metabolism to Promote Biofilm Formation
Riquelme SA, Liimatta K, Wong Fok Lung T, Fields B, Ahn D, Chen D, Lozano C, Sáenz Y, Uhlemann AC, Kahl BC, Britto CJ, DiMango E, Prince A. Cell Metabolism. 2020 Jun 2;31(6):1091-1106.e6. doi: 10.1016/j.cmet.2020.04.017. Epub 2020 May 18. PMID: 32428444
Urinary Defense Begins in the Kidney
Shen T, Levitman A, Li Y, Jacobs M, Xu K, Barasch J. Kidney International. 2019 Sep;96(3):537-539. doi: 10.1016/j.kint.2019.03.031. PMID: 31445577 Free PMC article.
Molecular Nephrology: Types of Acute Tubular Injury
Desanti De Oliveira B, Xu K, Shen TH, Callahan M, Kiryluk K, D'Agati VD, Tatonetti NP, Barasch J, Devarajan P. Nature Reviews 2019 Oct;15(10):599-612. doi: 10.1038/s41581-019-0184-x. Epub 2019 Aug 22. PMID: 31439924 Free PMC article. Review.
Transfusional Iron Overload and Intravenous Iron Infusions Modify the Mouse Gut Microbiota Similarly to Dietary Iron
La Carpia F, Wojczyk BS, Annavajhala MK, Rebbaa A, Culp-Hill R, D'Alessandro A, Freedberg DE, Uhlemann AC, Hod EA. NPJ Biofilms Microbiomes. 2019 Sep 24;5(1):26. doi: 10.1038/s41522-019-0097-2. eCollection 2019. PMID: 31583109.
Multidrug-Resistant Klebsiella pneumoniae ST307 in Traveler Returning from Puerto Rico to Dominican Republic
Rojas R, Macesic N, Tolari G, Guzman A, Uhlemann AC. Emerg Infect Dis. 2019 Aug;25(8):1583-1585. doi: 10.3201/eid2508.171730. PMID: 31310203 Free PMC article.
Escherichia coli Harboring mcr-1 in a Cluster of Liver Transplant Recipients: Detection through Active Surveillance and Whole-Genome Sequencing
Macesic N, Khan S, Giddins MJ, Freedberg DE, Whittier S, Green DA, Furuya EY, Verna EC, Annavajhala MK, Gomez-Simmonds A, Uhlemann AC. Antimicrob Agents Chemother. 2019 May 24;63(6):e02680-18. doi: 10.1128/AAC.02680-18. Print 2019 Jun. PMID: 30962343 Free PMC article.
Multidrug-Resistant Enterobacter cloacae Complex Emerging as a Global, Diversifying Threat
Annavajhala MK, Gomez-Simmonds A, Uhlemann AC. Front Microbiol. 2019 Jan 31;10:44. doi: 10.3389/fmicb.2019.00044. eCollection 2019. PMID: 30766518 Free PMC article.
Pparg Promotes Differentiation and Regulates Mitochondrial Gene Expression in Bladder Epithelial Cells
Liu C, Tate T, Batourina E, Truschel ST, Potter S, Adam M, Xiang T, Picard M, Reiley M, Schneider K, Tamargo M, Lu C, Chen X, He J, Kim H, Mendelsohn CL. Nature Commun. 2019 Oct 9;10(1):4589. doi: 10.1038/s41467-019-12332-0. PMID: 31597917 Free PMC article.
The Burden of Candidate Pathogenic Variants for Kidney and Genitourinary Disorders Emerging From Exome Sequencing
Rasouly HM, Groopman EE, Heyman-Kantor R, Fasel DA, Mitrotti A, Westland R, Bier L, Weng C; Zhong Ren Z, Copeland B, Krithivasan P, Sanna-Cherchi S, Goldstein DB*, Gharavi AG. Ann Intern Med 2019;170(1):11-21.
The Genomic Landscape of Congenital Anomalies of the Kidney and Urinary Tract
Verbitsky M, Westland R, Perez A, Kiryluk K, Liu Q, Krithivasan P, Mitrotti A, Fasel DA, Batourina E, Sampson MG, Bodria M, Werth M, Kao C, Martino J, Capone VP, Vivante A, Shril S, Kil BH, Marasa M, Zhang JY, Na YJ, Lim TY, Ahram D, Weng PL, Einzen EL, Carrea A, Piaggio G, Gesualdo L, Manca V, Masnata G, Gigante M, Cusi D, Izzi C, Scolari F, van Wijk JAE, Saraga M, Santoro D, Conti G, Zamboli P, White H, Drozdz D, Zachwieja K, Miklaszewska M, Tkaczyk M, Tomczyk D, Krakowska A, Sikora P, Jarmoliński T, Borszewska-Kornacka MK, Pawluch R, Szczepanska M, Adamczyk P, Mizerska-Wasiak M, Krzemien G, Szmigielska A, Zaniew M, Dobson MG, Darlow JM, Puri P, Barton DE, Furth SL, Warady BA, Gucev Z, Lozanovski VJ, Tasic V, Pisani I, Allegri L, Rodas LM, Campistol JM, Jeanpierre C, Alam S, Casale P, Wong CS, Lin F, Miranda DM, Oliveira EA, Sim√µes-e-Silva AC, Barasch JM, Levy B, Wu N, Hildebrandt F, Ghiggeri GM, Latos-Bielenska A, Materna-Kiryluk A, Zhang F, Hakonarson H, Papaioannou VE*, Mendelsohn CL*, Gharavi AG*, and Sanna-Cherchi S*. Nature Genetics. 2019 51:117-127.
Genetics Basis of Human Congenital Defects of the Kidney and Urinary Tract
Sanna-Cherchi S, Westland R, Ghiggeri GM, Gharavi AG*. Journal of Clinical Investigation, 2018 128(1):4-15.
BacCapSeq: a Platform for Diagnosis and Characterization of Bacterial Infections
Allicock OM, Guo C, Uhlemann AC, Whittier S, Chauhan LV, Garcia J, Price A, Morse SS, Mishra N, Briese T, Lipkin WI. mBio. 2018 Oct 23;9(5):e02007-18. doi: 10.1128/mBio.02007-18. PMID: 30352937 Free PMC article.