Publications
Polyploid Superficial Cells that Maintain the Urothelial Barrier Are Produced via Incomplete Cytokinesis and Endoreplication
Wang J, Batourina E, Schneider K, Souza S, Swayne T, Liu C, George CD, Tate T, Dan H, Wiessner G, Zhuravlev Y, Canman JC, Mysorekar IU, Mendelsohn CL. Cell Rep. 2018 Oct 9;25(2):464-477.e4. doi: 10.1016/j.celrep.2018.09.042. PMID: 30304685 Free PMC article.
In Vivo Replacement of Damaged Bladder Urothelium by Wolffian Duct Epithelial Cells
Joseph DB, Chandrashekar AS, Abler LL, Chu LF, Thomson JA, Mendelsohn C, Vezina CM. Proc Natl Acad Sci U S A. 2018 Aug 14;115(33):8394-8399. doi: 10.1073/pnas.1802966115. Epub 2018 Jul 30. PMID: 30061411 Free PMC article.
Exome-Wide Association Study Identifies GREB1L Mutations in Congenital Kidney
Sanna-Cherchi S*, Khan K, Westland R, Krithivasan P, Fievet L, Rasouly HM, Ionita-Laza I, Capone VP, Fasel DA, Kiryluk K, Kamalakaran S, Bodria M,. Otto EA, Sampson MG, Gillies CE, Vega-Warner V, Vukojevic K, Pediaditakis I, Makar GS, Mitrotti A, Verbitsky M, Martino J, Goj V, Na, YJ, Ardissino G, Gigante M, Gesualdo L, Zaniew M, Legutko M, Mendelsohn CL, Shril S, Hildebrandt F, van Wijk JA, Arapovic A, Saraga M, Allegri L, Izzi C, Scolari F, Tasic V, Ghiggeri GM, Latos-Bielenska A, Materna-Kiryluk A, Goldstein DB, Lifton RP, Katsanis N, Davis EE*, and Gharavi AG*. Malformations Am. J. Hum. Genet. 2017, 101(5):789-802
Genetic Drivers of Kidney Defects in the DiGeorge Syndrome
Lopez-Rivera E, Liu YP, Verbitsky M, Anderson BR, Capone VP, Otto EA, Yan Z, Mitrotti A, Martino J, Steers NJ, Fasel DA, Vukojevic K, Deng R, Racedo SE, Liu Q, Werth M, Westland R, Vivante A, Makar GS, Bodria M, Sampson MG, Gillies CE, Vega-Warner V, Maiorana M, Petrey DS, Honig B, Lozanovsk VJ, Salomon R, Heidet L, Carpentier W, Gaillard D, Carrea A, Gesualdo L, Cusi D, Izzi C, Scolari F van Wijk JA, Arapovic A, Saraga-Babic M, Saraga M, Kunac N, Samii A, McDonald-McGinn DM, Crowley TB, Zackai EH, Drozdz D, Miklaszewska M, Tkaczyk M, Sikora P, Szczepanska M, Mizerska-Wasiak M, Krzemien G, Szmigielska A, Zaniew M, Darlow JM, Puri P, Barton D, Casolari E, Furth SL, Warady BA, Gucev Z, Hakonarson H, Flogelova H, Tasic V, Latos-Bielenska A, Materna-Kiryluk A, Allegri L, Wong CS, Drummond IA, D'Agati V, Imamoto A, Barasch JM, Hildebrandt F, Kiryluk K, Lifton RP, Morrow BE, Jeanpierre C, Papaioannou VE, Ghiggeri GM, Gharavi AG, Katsanis N, Sanna-Cherchi S. New England Journal of Medicine. 2017 376(8):742-754.
Urinary Neutrophil Gelatinase-Associated Lipocalin for the Diagnosis of Urinary Tract Infections
Lubell TR, Barasch JM, Xu K, Ieni M, Cabrera KI, Dayan PS. Pediatrics. 2017. 140(6):e20171090. doi: 10.1542/peds.2017-1090. Epub 2017 Nov 16. PMID: 29146619 Free PMC article.
Transcription Factor TFCP2L1 Patterns Cells in the Mouse Kidney Collecting Ducts
Werth M, Schmidt-Ott KM, Leete T, Qiu A, Hinze C, Viltard M, Paragas N, Shawber CJ, Yu W, Lee P, Chen X, Sarkar A, Mu W, Rittenberg A, Lin CS, Kitajewski J, Al-Awqati Q, Barasch J. Elife. 2017 Jun 3;6:e24265. doi: 10.7554/eLife.24265. PMID: 28577314 Free PMC article.
Urinary NGAL Deficiency in Recurrent Urinary Tract Infections
Forster CS, Johnson K, Patel V, Wax R, Rodig N, Barasch J, Bachur R, Lee RS. Pediatr Nephrol. 2017 Jun;32(6):1077-1080. doi: 10.1007/s00467-017-3607-6. Epub 2017 Feb 16.PMID: 28210838 Free PMC article.
Characterization of a Murine Model of Bioequivalent Bladder Wound Healing and Repair Following Subtotal Cystectomy
Zarifpour M, Andersson KE, Kelkar SS, Mohs A, Mendelsohn C, Schneider K, Marini F, Christ GJ. Biores Open Access. 2017 May 1;6(1):35-45. doi: 10.1089/biores.2017.0011. eCollection 2017. PMID: 28560089 Free PMC article.
Carbapenem-resistant Enterobacteriaceae Colonization (CRE) and Subsequent Risk of Infection and 90-day Mortality in Critically Ill Patients, an Observational Study
McConville TH, Sullivan SB, Gomez-Simmonds A, Whittier S, Uhlemann AC. PLoS One. 2017 Oct 12;12(10):e0186195. doi: 10.1371/journal.pone.0186195. eCollection 2017. PMID: 29023567 Free PMC article.
Detection of mcr-1-Carrying Escherichia coli Causing Bloodstream Infection in a New York City Hospital: Avian Origins, Human Concerns?
Macesic N, Green D, Wang Z, Sullivan SB, Shim K, Park S, Whittier S, Furuya EY, Gomez-Simmonds A, Uhlemann AC. Open Forum Infect Dis. 2017 May 20;4(3):ofx115. doi: 10.1093/ofid/ofx115. eCollection 2017 Summer. PMID: 28721352 Free PMC article.
Multicenter Clinical and Molecular Epidemiological Analysis of Bacteremia Due to Carbapenem-Resistant Enterobacteriaceae (CRE) in the CRE Epicenter of the United States
Satlin MJ, Chen L, Patel G, Gomez-Simmonds A, Weston G, Kim AC, Seo SK, Rosenthal ME, Sperber SJ, Jenkins SG, Hamula CL, Uhlemann AC, Levi MH, Fries BC, Tang YW, Juretschko S, Rojtman AD, Hong T, Mathema B, Jacobs MR, Walsh TJ, Bonomo RA, Kreiswirth BN. Antimicrob Agents Chemother. 2017 Mar 24;61(4):e02349-16. doi: 10.1128/AAC.02349-16. Print 2017 Apr.PMID: 28167547 Free PMC article.
A Mucosal Imprint Left by Prior Escherichia Coli Bladder Infection Sensitizes to Recurrent Disease.
O'Brien VP, Hannan TJ, Yu L, Livny J, Roberson ED, Schwartz DJ, Souza S, Mendelsohn CL, Colonna M, Lewis AL, Hultgren SJ. Nature Microbiol. 2016 Oct 31;2:16196. doi: 10.1038/nmicrobiol.2016.196. PMID: 27798558 Free PMC article.
Disposal of Iron by a Mutant Form of Lipocalin 2
Barasch J, Hollmen M, Deng R, Hod EA, Rupert PB, Abergel RJ, Allred BE, Xu K, Darrah SF, Tekabe Y, Perlstein A, Wax R, Bruck E, Stauber J, Corbin KA, Buchen C, Slavkovich V, Graziano J, Spitalnik SL, Bao G, Strong RK, Qiu A. Nature Commun. 2016 Oct 31;7:12973. doi: 10.1038/ncomms12973. PMID: 27796299 Free PMC article.
Evidence From a New York City Hospital of Rising Incidence of Genetically Diverse Carbapenem-resistant Enterobacter cloacae and Dominance of ST171, 2007-14
Gomez-Simmonds A, Hu Y, Sullivan SB, Wang Z, Whittier S, Uhlemann AC. J Antimicrob Chemother. 2016 Aug;71(8):2351-3. doi: 10.1093/jac/dkw132. Epub 2016 Apr 26. PMID: 27118776.
Copy Number Variation Analysis Identifies Novel CAKUT Candidate Genes in Children With a Solitary Functioning Kidney
Westland R, Verbitsky M, Vukojevic K, Perry BJ, Fasel DA, Zwijnenburg PJ, Bökenkamp A, Gille JJ, Saraga-Babic M, Ghiggeri GM, D'Agati VD, Schreuder MF, Gharavi AG, van Wijk JA, Sanna-Cherchi S. Kidney Int. 2015;88(6):1402-1410.
Genomic Imbalances in Pediatric Patients With Chronic Kidney Disease
Verbitsky M, Sanna-Cherchi S, Fasel, A, Levy B, Kiryluk, K, Wuttke M, Abraham AG, Kaskel F, Köttgen, A, Warady BA, Furth SL, Wong CS, Gharavi AG. J. Clin Invest 2015: 125:2171-8
An Illustrated Anatomical Ontology of the Developing Mouse Lower Urogenital Tract
Georgas KM, Armstrong J, Keast JR, Larkins CE, McHugh KM, Southard-Smith EM, Cohn MJ, Batourina E, Dan H, Schneider K, Buehler DP, Wiese CB, Brennan J, Davies JA, Harding SD, Baldock RA, Little MH, Vezina CM, Mendelsohn C. Development. 2015 May 15;142(10):1893-908. doi: 10.1242/dev.117903. Epub 2015 May 12. PMID: 25968320 Free PMC article.
Urinary Neutrophil Gelatinase-Associated Lipocalin: Potential Biomarker for Late-Onset Sepsis
Pynn JM, Parravicini E, Saiman L, Bateman DA, Barasch JM, Lorenz JM. Pediatric Res. 2015 Jul;78(1):76-81. doi: 10.1038/pr.2015.62. Epub 2015 Mar 25. PMID: 25806716
The Ligands of Neutrophil Gelatinase-Associated Lipocalin
Bao GH, Ho CT, Barasch J. Royal Society of Chemistry Advances. 2015; 5(126):104363-104374. doi: 10.1039/C5RA18736B. Epub 2015 Dec 3. PMID: 27617081 Free PMC article.
Formation and Regeneration of the Urothelium
Yamany T, Van Batavia J, Mendelsohn C. Curr Opin Organ Transplant. 2014 Jun;19(3):323-30. doi: 10.1097/MOT.0000000000000084. PMID: 24752063 Review.