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1.0 2021-02-17 https://static1.squarespace.com/static/5f8db4e36f657d1433218347/t/5f8dba921815735846f9c867/1613492295677/cathy-mendelsohn.jpg Home - Cathy Mendelsohn https://static1.squarespace.com/static/5f8db4e36f657d1433218347/t/5f8dba33fa700d7a72592473/1613492244780/ali-gharavi.jpg Home - Ali G. Gharavi https://static1.squarespace.com/static/5f8db4e36f657d1433218347/t/5f8dbadb18301633ba4b503c/1613492258108/anne-catrin-uhlemann.jpg Home - Anne-Catrin Uhlemann https://static1.squarespace.com/static/5f8db4e36f657d1433218347/t/5f8db9ce06e3f27d9dfae4f4/1613492209283/jon-barasch.jpg Home - Jonathan Barasch https://columbiabenignurology.com/project-one daily 0.75 2021-02-16 https://static1.squarespace.com/static/5f8db4e36f657d1433218347/t/602aa8da42da9410c1819ea6/1613408486027/gharavi-latest-hot-stuff.png Project One Figure. Regional association plots for loci associated with VUR. The calculated -log10 P values are shown according to genomic position (hg19). The most significant SNP is colored purple. Other colors indicate LD (r2; see inset) to top SNP, based on the 1000 Genomes European sample set. https://static1.squarespace.com/static/5f8db4e36f657d1433218347/t/602a9e409b92b8400e351102/1613496306567/project-one.png Project One Figure. Concentric Manhattan plot showing mapping of new risk loci for VUR via GWAS (L). Excess burden of large CNVs in VUR (R). https://columbiabenignurology.com/project-two daily 0.75 2021-09-24 https://static1.squarespace.com/static/5f8db4e36f657d1433218347/t/6029a246c6bed064bd3f22ec/1613405414557/project-two.png Project Two Gene expression changes in the urothelium of Pparg mutants. A heatmap showing changes in expression of genes related to mitochondrial functions in ShhCre; Ppargfl/fl mutants compared to controls. https://static1.squarespace.com/static/5f8db4e36f657d1433218347/t/602ae5551ac7f35995451f24/1613424037573/mendelsohn-latest-hot-stuff.png Project Two A-D. Urothelium from a control mouse stained for expression of Fabp4, K20, K14 and Pparg. E-J. K5CreERT2;VP16Pparg mutant urothelium stained with Fabp4, K20, K14 and Pparg. https://columbiabenignurology.com/project-three daily 0.75 2021-02-16 https://static1.squarespace.com/static/5f8db4e36f657d1433218347/t/602aea19eb1147168bc19f51/1613425203641/project-three.png Project Three Figure. Superfical Cells Metabolize Heme. Slc48a1=Heme Capture; HO1=Heme Mebolism; CO is released into the Bladder Lumen https://static1.squarespace.com/static/5f8db4e36f657d1433218347/t/602aeabf7a57d9350d87b19a/1613425388421/barasch-latest-hot-stuff.png Project Three https://columbiabenignurology.com/project-four daily 0.75 2021-02-16 https://static1.squarespace.com/static/5f8db4e36f657d1433218347/t/602ae84a10a23e723d42d652/1613424740613/project-four.png Project Four Figure. Overview of MGBC Services. https://static1.squarespace.com/static/5f8db4e36f657d1433218347/t/602ae8c072b86832437e77ad/1613424853329/uhlemann-latest-hot-stuff.png Project Four Figure. A. Microbiome composition in participants with (yes) and without toilet training (no) B. There are significant differences in alpha diversity C. Sequence distance (Unifrac) D. There is a significant enrichment in enterococcus species in the samples from patients without toilet training. https://columbiabenignurology.com/ali-gharavi daily 0.75 2021-02-16 https://static1.squarespace.com/static/5f8db4e36f657d1433218347/t/6029b0651ac7f359952e0e0a/1613344889444/ali-gharavi.jpg Investigators: Ali Gharavi https://columbiabenignurology.com/cathy-mendelsohn daily 0.75 2021-02-16 https://static1.squarespace.com/static/5f8db4e36f657d1433218347/t/6029b0f8c1889644fc1aedf7/1613345029786/cathy-mendelsohn.jpg Investigators: Cathy Mendelsohn https://columbiabenignurology.com/students daily 0.75 2021-09-24 https://static1.squarespace.com/static/5f8db4e36f657d1433218347/t/6029b3235246cb1b629cea86/1613345594431/summer-program-students.png Students https://columbiabenignurology.com/opportunities daily 0.75 2021-09-24 https://static1.squarespace.com/static/5f8db4e36f657d1433218347/t/602a8b0cdf6c9f16ca8308bd/1613400871377/opportunity-pool.png Opportunities https://columbiabenignurology.com/symposium daily 0.75 2021-09-24 https://columbiabenignurology.com/resources daily 0.75 2021-09-24 https://columbiabenignurology.com/jonathan-barasch daily 0.75 2021-02-16 https://static1.squarespace.com/static/5f8db4e36f657d1433218347/t/602ae68cf0571f68b018d6c0/1613424280966/jon-barasch.jpg Jonathan Barasch https://columbiabenignurology.com/anne-catrin-uhlemann daily 0.75 2021-02-16 https://static1.squarespace.com/static/5f8db4e36f657d1433218347/t/602ae70542da9410c18957c6/1613424412531/anne-catrin-uhlemann.jpg Investigators: Anne-Catrin Uhlemann